小鼠细菌性乳腺炎模型研究进展

Research Progress of Bacterial Mastitis Model in Mice

关键词:  鼠  急性乳腺炎  慢性乳腺炎  金黄色葡萄球菌  小菌落突变

Key words:  mice  acute mastitis  chronic mastitis  Staphylococcus aureus  small colony variants

摘要:

奶牛细菌性乳腺炎一直是困扰奶牛养殖业的一大难题，给奶牛养殖行业造成巨大经济损失，直接危害奶牛健康。为有效治疗奶牛细菌性乳腺炎，研究人员需要通过动物模型来进行相关研究，以期找到优良的治疗方法。随着动物模型多年的探索与使用，小鼠细菌性乳腺炎模型因具有省时、省力以及性价比高的优点获得了研究人员的广泛认可，被大量用于相关研究中。就此对小鼠细菌性乳腺炎模型的建立、特点以及应用进行综述，旨在为细菌性乳腺炎相关研究提供参考。

Abstract:

Bacterial mastitis has always been a major problem in the dairy industry, which has caused huge economic losses and directly endangered the health of dairy cows. In order to effectively treat cow bacterial mastitis, researchers need to carry out relevant research through animal models in order to find an excellent treatment method. With the exploration and use of animal models for many years, bacterial mouse mastitis model has been widely recognized by researchers. Because of its advantages of time-saving, labor-saving and cost-effective, this model has been widely used in related research. In this paper, the establishment, characteristics and application of bacterial mouse mastitis model were reviewed in order to provide reference for the related research of bacterial mastitis.