基于纳米材料的免疫层析试纸在兽药残留检测中的应用

Application of immunochromatographic assay strip based on nanomaterials in veterinary drug residues detection

关键词:  免疫层析试纸  兽药残留  胶体金  磁性纳米材料  量子点  时间分辨荧光微球

Key words:  immunochromatographic assay strip  veterinary drug residue  colloidal gold  magnetite nanoparticles  quantum dots  time-resolved fluorescence microsphere

摘要:

兽药残留是食品安全的重要影响因素，开发兽药残留检测方法是保证食品安全的重要手段。免疫层析试纸是一种操作简单、生产成本低且具有良好灵敏度的检测方法，适用于现场检测、大规模食品筛选，在兽药残留检测中具有巨大的应用价值。纳米材料可提供特殊的检测信号，是影响免疫层析试纸检测灵敏度和定量分析的关键因素。文章主要对胶体金、磁性纳米材料、量子点以及时间分辨荧光微球这几种纳米标记材料进行介绍，指出各自的优缺点及应用情况，并对该技术在兽药残留检测中的应用趋势进行展望。

Abstract:

Veterinary drug residues are an important factor affecting food safety, developing veterinary drug residue detection methods is an important means to ensure food safety. Immunochromatographic assay strip is a detection method with simple operation, low production cost and good sensitivity. It is suitable for on-site detection and large-scale food screening, and has great application value in veterinary drug residue detection. Nanomaterials can provide special signals, which are the key factors affecting the detection sensitivity and quantitative analysis of immunochromatographic assay strip. The article mainly introduces several nano-labeled materials such as colloidal gold, magnetic nanomaterials, quantum dots and time-resolved fluorescent microspheres, points out their advantages, disadvantages and applications, forecasts the application trend of this technology in veterinary drug residues detection.