猫泛白细胞减少症疫苗的研究进展

Progress on Feline Panleukopenia Vaccine

关键词:  猫泛白细胞减少症；疫苗  研究进展

Key words:  Feline Panleukopenia  Vaccine  Progress

摘要:

猫泛白细胞减少症是由猫泛白细胞减少症病毒引起的，猫科动物常见的接触性传染病之一，临床发病率和死亡均较高，疫苗免疫是预防和控制该病最经济、最直接的措施。然而，国内几无商业化宠物疫苗，特别是猫用疫苗，国外疫苗进口困难，亟需开发新型宠物用高效疫苗。本研究拟对不同类型疫苗（灭活疫苗、减毒活疫苗等）的优缺点、国内、外研究进展以及国外此类疫苗现状进行综述与分析，为开发宠物用新型、高效生物制品提供基础数据。

Abstract:

Feline panleukopenia, caused by feline panleukopenia virus (FPV), is a highly contagious infectious disease that characterized by leucopenia and hemorrhagic gastroenteritis, which severely affects the health of cat or large wild Felidae. Vaccine immunization is the most economical and direct measurement to prevent and control the disease. However, there is almost no commercialized pet vaccine in domestic, especially for cats, and foreign vaccine were difficult to imported for the pandemic of COVID-19, so a highly effective vaccines for pet use were urgent needed. In this paper, the research status and problems concerning FPV vaccine, either domestic or abroad, which including inactivated vaccine, attenuated live vaccine and live vector vaccine, were summarized. Meanwhile, the information about commercial FPV vaccine circulated in abroad market were also summarized. So as to provide some useful reference for subsequent study of vaccine against FPV.