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安乃近在羊组织中最大残留限量标准制定研究
安肖,徐士新*,杨曙明*,郝利华
0
(中国兽医药品监察所;中国农业科学院)
摘要:
安乃近是一种吡唑酮类非甾体解热抗炎药,在我国和欧洲许多国家普遍应用于兽医临床治疗动物发热性疾病。本研究依据安乃近在羊组织中代谢和消除实验数据,比较讨论了国际食品法典、美国、欧盟关于兽药残留限量标准的制定程序和结果的差异,建议采纳欧盟方法计算并设定安乃近在羊组织中的最大残留限量为100 μg/kg(以残留标示物MAA计算)。
关键词:  安乃近    最大残留限量
DOI:
投稿时间:2020-07-24修订日期:2020-09-28
基金项目:农业部农业行业标准制修订科研专项:安乃近在羊组织中的最大残留限量标准制定研究
Study on Drafting Maximum Residue Limits of Dipyrone in Goat
(China Institute of Veterinary Drug Control)
Abstract:
Dipyrone(Metamizole)is a kind of pyrazolone non-steroidal anti-inflammatory drug (NSAID), which is widely applied in clinical treatment for animal febrile illness in China and many European countries. In this research, based on the metabolism and depletion study of dipyrone in goat tissues, the MRLs establishment procedures of the Codex Alimentarius Commission, the United States and the European Union have been compared and discussed, and the MRLs of dipyrone in goat tissues were recommended as 100 μg/kg (calculated as the marker residue MAA) according to EU method.
Key words:  Dipyrone, Goat, Maximum Residue Limit

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