犬椎间盘病治疗中常用抗炎药物合理应用研究

Analysis of Rational Use of Commonly Used Anti-inflammatory Drugs in Clinic for Canine Intervertebral Disc Disease

关键词:  犬  椎间盘病  抗炎疗法  糖皮质激素  非甾体类抗炎药

Key words:  canine  intervertebral disc disease  anti-inflammatory therapy  glucocorticoid  non- steroid anti- inflammatory drugs

摘要:

犬椎间盘病（IVDD）继发性损伤中的炎症反应过程复杂，临床中如何选用相应药物成为了治疗难点。目前临床常用的两大类用于椎间盘病抗炎治疗的药物包括甾体类与非甾体类抗炎药（NSAIDs），它们的使用一直以来存在很大的争议。因此，了解它们各自的药理特性十分重要，本文结合这两大类药物作用机制及疗效研究展开了对二者的合理用药分析，以期为临床IVDD抗炎药物的选用提供一定参考。

Abstract:

Because of the complicated inflammatory response process of secondary injury in the course of canine intervertebral disc disease(IVDD), there is a therapeutic difficulty in how to choose anti-inflammatory drugs in the clinic for canine IVDD. At present, two kinds of anti-inflammatory drugs, glucocorticoid and non-steroid anti-inflammatory drugs are commonly used in the clinic, but the evaluations of treatment effects of them are widely disputed. So it is necessary to understand the features and rational use of these two types of drugs. This paper analyzes the rational use of these two drugs by means of combining their mechanism with effect study. Hopefully this will provide some references for the clinic treatment of inflammation in canine IVDD.