中草药对细菌耐药质粒的消除作用研究

Study on elimination of bacterial drug resistant plasmids by Chinese herbs

关键词:  中草药  耐药性  质粒消除

Key words:  Chinese herbal medicine  Drug resistance  Plasmid elimination

摘要:

动物养殖中常见病原菌对抗菌药物的耐药性呈逐年上升的趋势,引起了广大科研工作者的极大关注。病原菌耐药性的产生主要与质粒有关,质粒能够将耐药基因传递给环境中的其他细菌,进而引起多重耐药菌株的出现。本文就细菌耐药现状、细菌耐药性与质粒关系、中草药对细菌耐药质粒的消除效果、中草药消除耐药质粒的机理、存在的问题、中草药对耐药质粒消除的展望这些方面进行简单综述。

Abstract:

The resistance of common pathogenic bacteria to antibacterial drugs in animal breeding has been increasing year by year, which has aroused the great concern of researchers. The generation of drug resistance of pathogens is mainly related to plasmids. Plasmids can transmit drug resistance genes to other bacteria in the environment, causing the emergence of multiple drug-resistant strains. This article briefly reviews the current status of bacterial drug resistance, the elimination effects of Chinese herbal medicines on bacterial drug resistance plasmids, the mechanism of elimination of resistant plasmids by Chinese herbal medicines, existing problems, and the prospects for elimination of drug resistant plasmids by Chinese herbs.