| 摘要: |
| 简要阐述主要组织相容性复合体(MHC)Ⅰ类分子递呈抗原过程,分析病毒干扰MHC-Ⅰ类分子抗原递呈所采取的策略,以期揭示病毒的免疫逃逸机制,为病毒疫苗的研制提供一定的思路。 |
| 关键词: 主要组织相容性复合体Ⅰ类分子 抗原递呈 病毒 免疫逃逸 |
| DOI： |
| 投稿时间：2016-12-29修订日期：2017-04-09 |
| 基金项目:北京市科技计划项目(D151100002515003) |
|
| MHC-ⅠAntigen Presentation and Viral Immune Evasion |
|
| (China Institute of Veterinary Drug Control) |
| Abstract: |
| This paper describes the progress of antigen presentation mediated by major histocompatibility complexⅠ(MHC-Ⅰ)molecule, as well as the countermeasures and specific molecular mechanisms exploited by viruses to evade this type of immunity, which are helpful for understanding the mechanisms associated with viral immune evasion and contribute to the development of viral vaccines. |
| Key words: major histocompatibility complexⅠmolecule antigen presentation virus immune evasion |
