维他昔布片对猫血液学指标的影响研究

Effect of Vitacoxib Pellet on the Haematological Indexes in Cats

关键词:  维他昔布  猫  血常规检查  血生化检查

Key words:  vitacoxib  cat  blood routine examination  serum biochemical examination

摘要:

为评价维他昔布片对猫的安全性，将本地24只健康家猫随机分为4组，分别为空白组（2 mg/kg）、罗贝考昔对照组（2 mg/kg）、维他昔布1倍推荐剂量组（2 mg/kg）、维他昔布3倍推荐剂量组（6 mg/kg），每组6只，连续给药14 d。于给药前及给药后7、14 d测定猫的体温、体重、血常规及血生化指标。试验结果表明，给药前后猫的体温、体重和临床表现正常，各试验组间的血常规及血生化指标无显著差异性。说明维他昔布片对猫的血液学变化无显著性影响，用药安全。

Abstract:

In order to evaluate the safety of vitacoxib pellets to cats, twenty-four local healthy cats were randomly divided into four treatment groups, 6 in each group, these groups were respectively the blank group(2 mg/kg), the control group of robenacoxib (2 mg/kg), 1 and 3 times the recommended dose group of vitacoxib(2 mg/kg, 6 mg/kg), for 14 days continuously. Then the body temperatures、body weights、blood routine and serum biochemical indexes were measured on 0, 7, 14 days after the first administration. The results indicated that the cats’ body temperatures, body weights and clinical manifestations of normal, blood routine and serum biochemical indexes of each experimental group were no significant difference between pre-dose and after treaded. It indicated that vitacoxib pellet had no significant effects on the changes of the hematology in cats, vitacoxib could be used safely.