肥猪散发酵制剂的药效学研究

Study on Pharmacodynamics of Feizhusan Fermentation Preparation

关键词:  肥猪散发酵制剂  药效学  胃蛋白酶  小肠推进试验

Key words:  feizhusan fermentation preparation  pharmacodynamics  pepsase  intestinal movement experiment

摘要:

利用人工制造消化不良病理模型考察肥猪散发酵制剂对消化不良家兔的体重、进食、胃酸和胃蛋白酶的影响以及小肠推进实验考察肥猪散发酵制剂对正常小鼠的小肠推进速度的影响。结果显示：肥猪散发酵制剂增加消化不良家兔模型的体重、进食量，调整胃酸量和胃蛋白酶的活性，加快小鼠的小肠推进速度，中剂量组的药效可达到普通散剂的2倍。肥猪散发酵制剂促进了肥猪散消食开胃的作用，本实验为肥猪散发酵制剂的药效学研究提供了参考。

Abstract:

To evaluate the pharmacodynamic effects of feizhusan fermentation preparation on appetite and digestion，the effection on body weight, feeding, gastric acid and pepsase of rabbits was inspected by inducing pathological model of dyspepsia on healthy animals and the effection on intestinal peristalsis of mice was observed by intestinal movement experiment. Results indicated that feizhusan fermentation preparation could increase the body weight and food intake of dyspepsia rabbits, regulate the gastric acid and the pepsase, promote the movement of small intestine. The fermentation process doubled the pharmacodynamic effects of ordinary powder. feizhusan fermentation preparation has more effect on stimulating appetite and digestion to feizhusan.