摘要: |
为研究β-胡萝卜素对小鼠免疫功能的影响,在基础日粮中添50mg/kg的β-胡萝卜素,使用环磷酰胺建立免疫抑制模型。最后观察免疫器官组织形态学变化,测定免疫器官指数,血清中细胞因子以及免疫球蛋白含量等指标。结果表明β-胡萝卜素能改善由环磷酰胺引起免疫器官的损伤,通过提高免疫抑制小鼠血清中的细胞因子和免疫球蛋白含量,增强机体免疫力。 |
关键词: β-胡萝卜素 免疫抑制模型 细胞因子 免疫球蛋白 |
DOI: |
投稿时间:2014-06-12修订日期:2014-07-07 |
基金项目:国际科技合作项目(20130413037GH);吉林省科技厅项目(20110224) |
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Effect of β-carotene on immune index of the immunosuppression mice |
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(College of Life Science,Jilin Agricultural University) |
Abstract: |
Mice were supplemented with 50mg/kg β-carotene and established an immunosuppression model by cyclophosphamide to study the effects of β-carotene on immune function in mice. The immune organs index,histomorphology of immune organs, cytokines and immunoglobulin in serum were detected to evaluate the role of β-carotene.The results showed that β-carotene can improve the immune organ damage caused by cyclophosphamide and the cytokine and immunoglobulin levels in serum of immunosuppression mice, also can improve the immune function. |
Key words: β-carotene,Immunosuppressive Model Cytokine,Immunoglobulin |