几种常用酸稀释液测定泰乐菌素精制液效价的方法比较

Comparison of Methods for Determination of Tylosin Concentrated Solution by Several Common Acid Dilution

关键词:  稀释液  泰乐菌素  效价

Key words:  dilution  tylosin  determination of titers

摘要:

分别采用0.1 mol/L盐酸溶液、0.05 mol/L硫酸溶液、0.033 mol/L磷酸溶液作稀释液测定泰乐菌素精制液化学效价，从曲线线性关系、准确度及检验结果对比方面进行分析比较。结果显示：三种溶液吸收度与浓度均呈良好的线性关系（R盐酸2=0.9997，R硫酸2=1.0000，R磷酸2=1.0000；n=5），准确度高，测定结果无明显差异，在质量控制中可以选择不同的酸稀释液进行测定。

Abstract:

The method used three diluted solutions, such as 0.1 mol/L hydrochloric acid solution, 0.05 mol/L sulfuric acid solution, 0.033 mol/L phosphoric acid solution, Determining of tylosin concentrated solution chemical titer for comparison respectively, from the curve of the linear relationship, accuracy and contrast test results were analyzed and compared.The results showed that three kinds of solution had a good linear relationship between absorbance and concentration.(RH2=0.9997，RS2=1.0000，RP2=1.0000；n=5); and high accuracy;Results had no significant difference. We can choose different acid dilutions for determination in quality control.