| 摘要: |
| 为制定更为合理的给药方案，防止细菌耐药性的过快增长，介绍了近年来给药方案对细菌耐药性选择性富增的影响的研究进展，认为防突变浓度和突变选择窗可能成为制定合理给药方案的新标准以及今后兽用抗菌药物研究的一个方向。
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| 关键词: 抗菌药物 耐药性 富增 防突变浓度 突变选择窗 |
| DOI： |
| 投稿时间：2012-11-09修订日期：2013-04-02 |
| 基金项目:国家自然科学基金（31172363）；公益性行业（农业）科研专项经费（201203085）；海南省教育厅项目（Hjkj2011-12） |
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| Review on the Relationship between the Usage of Antibacterials and the Accumulation of Resistance |
|
| (Agricultural College,Hainan University) |
| Abstract: |
| For formulating more rational dosage regimen and preventing the fast growth of resistance, the research progress on relationship between the usage of antibacterials and the accumulation of resistance was reviewed in this paper. Mutation prevention concentration and mutation selection windows maybe become the new standard that formulate dosage regimen, and become a new researching aspect of veterinary medicine. |
| Key words: antibacterials resistance accumulation mutation prevention concentration mutation selection windows |
