| 摘要: |
| 猪支原体肺炎灭活疫苗和弱毒活疫苗的临床应用均有很好的效果。简述了猪支原体肺炎灭活疫苗以体液免疫为主、弱毒活疫苗以细胞免疫和粘膜免疫为主的不同免疫学特性，分析认为占位效应可能是猪支原体肺炎弱毒活疫苗独特的免疫原理之一，提出了灭活疫苗可能的改良方向及保证弱毒疫苗高效免疫的三项措施，以期为猪支原体肺炎防控提供参考。 |
| 关键词: 猪支原体肺炎 灭活疫苗 弱毒活疫苗 应用效果 |
| DOI： |
| 投稿时间：2012-06-28修订日期：2012-07-23 |
| 基金项目:江苏省农业科技自主创新资金［cx(11)3025］；江苏省农业科学院博士后基金(6511101) |
|
| The Application of Mycoplasma Hyopneumoniae Inactivated Vaccine; and Attenuated Vaccine |
|
| (Institute of Veterinary Medicine, Jiangsu Academy of Agricultural Sciences. Key Laboratory of Veterinary Biological Engineering and Technology，Ministry of Agriculture . National Center for Engineering Research of Veterinary Bio-products) |
| Abstract: |
| There was a good result in the application of Mycoplasma hyopneumoniae inactivated vaccine and attenuated vaccine.In this paper, the immunological characteristics of inactivated vaccine which was mainly to humoral immunity and of attenuated vaccine which was to mucosal and cellular immune responses were introduced. The occupying effect may be one of a unique immune mechanism of attenuated vaccine.More important,an improvement direction of inactivated vaccine and three measures to ensure the efficient immune of attenuated vaccine were put forward in order to provide reference for the prevention and control of mycoplasma pneumonia of swine in the future. |
| Key words: Mycoplasma hyopneumoniae inactivated vaccine attenuated vaccine effectiveness |
