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氯苯胍在鸡组织中的残留消除规律研究
班付国,吴宁鹏
0
(河南省兽药监察所)
摘要:
采用超高效液相色谱-串联质谱法(UPLC-MS/MS)研究了氯苯胍在鸡组织中的残留消除规律。白来杭鸡以含氯苯胍500 mg/kg饲料饲喂7 d,停药后的第0、1、3、5、7天取其肌肉、肝脏、肾脏、皮和脂肪五种组织,采用UPLC-MS/MS法测定其残留状况。结果表明,氯苯胍在肌肉中残留量较小,代谢消除比较快,2 d后未检出;而在脂肪、皮和肝脏中残留量较大,代谢消除较慢。
关键词:  氯苯胍  鸡组织  残留消除
DOI:
投稿时间:2012-05-17修订日期:2012-07-04
基金项目:
Depletion of Robenidine Residue in Chicken Tissues
(Henan Institute of Veterinary Drug Control)
Abstract:
The depletion of robenidine residue in chicken tissues was studied by UPLC-MS/MS. After an oral dose of 500 mg per kilogram of robenidine for 7 days, the robenidine residue in chicken muscle was lower than that in other tissues, such as the fat,skin,kindey and liver,and it was not detected after 2 days. The results showed that robenidine in chicken tissues was of rapid absorption, and hard to be eliminate.
Key words:  robenidine  chicken tissues  residue depletion

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