| 摘要: |
| 皮下注射经复方煤焦油酸溶液灭活后的O型口蹄疫乳鼠组织毒（LD50=1?10-8.0）感染4日龄乳鼠，通过ELISA试验观察口蹄疫病毒感染乳鼠情况，考察韶山大北农动物药业有限公司生产的复方煤焦油酸溶液（农喜福）对O型口蹄疫乳鼠组织毒的杀灭效果。结果显示，农喜福1:600倍稀释液在室温条件下作用30分钟，能100%杀灭口蹄疫强毒，可用于口蹄疫病毒污染的动物栏舍，运载工具、环境等的消毒，在杀灭病毒、安全性等方面与国外同类产品相当。 |
| 关键词: 复方煤焦油酸溶液 消毒剂 口蹄疫病毒 杀灭作用 |
| DOI： |
| 投稿时间：2011-10-12修订日期：2011-12-21 |
| 基金项目: |
|
| The killing effect of Compound Tar Acids Solution against foot-and-mouth disease virus |
| Liiu Lan[sub_s][sub_e] |
| (DBN Animal Health Technology Research Center) |
| Abstract: |
| The purpose of this experiment was to determine the killing effect of Compound Tar Acids Solution disinfectant against foot-and-mouth disease virus（FMDV）. The 4-day-old mice were artificially infected by O type FMDV（LD50 =1?10-8.0）mixed with different concentrations of the disinfectants through subcutaneous injection route, then tested virus proliferation in vivo by ELISA. The results showed that FMDV mixed with 1:600 diluted disinfectant at room temperature in 30 minutes were completely inactivated. Compound Tar Acids Solution disinfectant manufactured by Shaoshan DBN Animal Pharmaceutical Co., Ltd. could be used for disinfection of animal pens, vehicles and environment to control FMD outbreak, and was equal to foreign similar product in antiviral, security and other aspects. |
| Key words: Compound Tar Acids Solution disinfectant foot-and-mouth disease virus killing effect |
