| 摘要: |
| 为了减少痢菌净的毒副作用及临床用药次数，本实验特制备痢菌净缓释纳米乳。方法：用水包油法制备痢菌净纳米乳，并对其形态、粒径、稳定性及体外释放等性能进行了一定的研究。结果：纳米乳的稳定性较好，平均粒径在50nm左右，80小时体外释放率达到70%，具备明显的缓释功能。结论：本研究获得了制备痢菌净纳米乳较为满意的工艺。 |
| 关键词: 痢菌净；纳米乳 缓释. |
| DOI： |
| 投稿时间：2010-11-12修订日期：2011-01-18 |
| 基金项目: |
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| Mequindox nanoemulsion preparation and determination of in vitro release |
| Feng xiao-hua |
| (Hunan Institute of Animal and Veterinary Science) |
| Abstract: |
| To reduce mequindox clinical medication side effects and the number of special preparation of the experiment mequindox release nanoemulsion. Methods: Preparation of oil-water mequindox nanoemulsion and its morphology, particle size, stability and in vitro release properties were so certain of. Results: The stability of nanoemulsion good average diameter of about 50nm, 80-hour in vitro release rate of 70%, with significant release function. Conclusion: The obtained nanoemulsion preparation mequindox the more satisfactory process. |
| Key words: Mequindox nanoemulsion release. |
