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7-氨基头孢烷酸分子印迹聚合物的制备及结合性能评价
张玲
0
(安徽农业大学)
摘要:
本实验以头孢类药物的母核7-氨基头孢烷酸为模板分子、4-乙烯基吡啶为功能单体在一定条件下合成7-氨基头孢烷酸分子印迹聚合物,用平衡结合实验研究了聚合物的结合性能。并研究了7-氨基头孢烷酸分子印迹聚合物对头孢类药物的选择性。结果表明,7-氨基头孢烷酸分子印迹聚合物对头孢类药物有很好的选择性,能够作为畜禽食品中头孢类药物萃取净化的分离材料。
关键词:  7-氨基头孢烷酸  分子印迹聚合物  头孢类药物
DOI:
投稿时间:2009-11-03修订日期:2010-01-11
基金项目:国家自然科学基金项目(面上项目,重点项目,重大项目)
7 - ACA Molecularly Imprinted Polymer Preparation and Combined with Performance Evaluation
zhangling
(Anhui Agricultural University)
Abstract:
To cephalosporin class of drugs Nucleus 7 - ACA as a template molecule,、4 - vinylpyridine as functional monomer synthesis under certain conditions, synthesized 7 - ACA molecularly imprinted polymers, equilibrium binding experiment with a combination of polymer properties.And study of the 7 - ACA molecularly imprinted polymer selectivity for cephalosporins drugs. The results showed that 7 - ACA molecularly imprinted polymer on the cephalosporin drugs have a good selectivity. It can be used as animal food cephalosporin drugs extraction separation of purification material.
Key words:  7 - ACA  molecularly imprinted polymer  cephalosporin drugs

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