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超高效液相色谱简介及应用比较
胡海燕
0
(中国兽医药品监察所)
摘要:
本文简要介绍了超高效液相色谱(UPLC)的技术特点和优势,并对磺胺类药物的测定进行了HPLC和UPLC两种条件下的分析比较,结果表明:UPLC方法的突出优点体现在节省分析时间和溶剂用量上,尤其对基质复杂的痕量组分测定采用UPLC方法以提高分析通量是今后发展的必然趋势。
关键词:  超高效液相色谱  磺胺类药物  高效液相色谱  分析
DOI:
投稿时间:2009-09-08修订日期:2009-09-08
基金项目:
Introduction and Application Comparison of Ultra performance Liquid Chromatography
huhaiyan
(China Institute of Veterinary Drug Control)
Abstract:
This paper concisely introduced the technical characteristics and advantages of ultra performance liquid chromatography(UPLC), and compared the analysis results of sulfonamides drugs performed by HPLC and UPLC . The results showed that, the outstanding benefits of UPLC embodied in the saving analysis time and solvent consumption. in particular,when trace components of complex matrix were measured. therefore,it is the inevitable trend to improve the analysis of flux of trace components by using UPLC in the future.
Key words:  UPLC  sulfonamides drugs  HPLC  analysis

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