| 摘要: |
| 摘要：采用分子印迹技术，以α-甲基丙烯酸为功能单体，合成了对头孢噻肟具有选择结合能力的分子印迹聚合物。将制备的块状聚合物研磨过筛后，运用平衡结合试验研究了头孢噻肟分子印迹聚合物的结合性质。在所研究的浓度范围内，头孢噻肟分子印迹聚合物与相应的非模板聚合物相比，表现出很高的结合容量。底物选择性实验表明：与其他结构相似的药物相比，头孢噻肟分子印迹聚合物对头孢噻肟显示了很强的结合能力。 |
| 关键词: 头孢噻肟 分子印迹聚合物 |
| DOI： |
| 投稿时间：2008-11-17修订日期：2008-12-19 |
| 基金项目:国家“十一.五”科技支撑计划 |
|
| Preparation and Binding Characteristics of Molecularly Imprinted Polymers for Cefotaxime Sodium |
| hedongxu,陈玎玎 |
| () |
| Abstract: |
| Abstract: A kind of molecular imprinted polymer was prepared using Cefotaxime as the template molecule , MAA as functional monomer .The bulk polymer was ground up sieved and investigated in equilibrium binding experiment to evaluate the binding characteristic of the cefotaxime-imprinted polymer . The polymer gave much higher binding capacity for cefotaxime than the non-imprinted polymer.The selectivity was evaluated by cefotaxime and other compounds with similar structure .The results showed that the imprinted polymer exhibited high affinity for cefotaxime among the texted compounds . |
| Key words: Cefotaxime Molecular Imprinting Polymer |
