几种药物对奶牛附红细胞体的敏感性对比研究

The comparative study between several medicaments on eperythrozoonosis in cows

关键词:  附红细胞体  药物治疗  敏感药物

Key words:  Eperythrozoon  medication  hypersensitive medicament

摘要:

利用体外培养和豚鼠试验两个方法，筛选对奶牛附红细胞体较为敏感的药物。选取贝尼尔、咪唑苯脲、盐酸多西环素、磺胺间甲氧嘧啶四种药物，用牛附红细胞体阳性血液作为敏感药物筛选的载体，进行体外敏感药物筛选试验；用牛附红细胞体阳性血液感染健康豚鼠，感染率大于90％后，进行药物治疗试验。结果显示最为敏感药物是盐酸多西环素。

Abstract:

This experiment research the medicament on Eperythrozoonosis from two aspect---outer culture and cavy test, then filtering the hypersensitive medicament. Four medicament has been chosen Diminazene, Imidocarb Dipropionate，Sulfamonomethoxine and Doxycycline hydrochloride, the masculine Eperythrozoonosis blood of cow as carrier, cavy as test animal. From outer culture, Doxycycline hydrochloride is the hypersensitive medicament on Eperythrozoonosis, the second is Sulfamonomethoxine. The cavies appear clinical symptom after infected by the masculine Eperythrozoonosis blood of cow and their infection rate are all above 90%. The result shows that Doxycycline hydrochloride is the hypersensitive medicament on Eperythrozoonosis after medication on the cavies.