睡眠嗜血杆菌复合体病研究进展

The Research Progress on Hemophilosis

关键词:  睡眠嗜血杆菌  疾病

Key words:  Haemophilus somnus  Hemophilosis

摘要:

Haemophilus somnus has long been associated with thrombotic meningoencephalomyelitis but has also been identified as the agent responsible for other clinical diseases including respiratory disease, reproductive problems, myocarditis, otitis, conjunctivitis, mastitis, and polyarthritis. Exposure to the bacteria is widespread and infection may occur via the respiratory tract from urogenital excretions and secretions.Diagnosis and treatment of hemophilosis may be easy or difficult depending on the manifestation presented, and special procedures must be taken to facilitate isolation of the organism. vaccination is the only preventive measure demonstrating a beneficial effect.

Abstract:

睡眠嗜血杆菌属于变形杆菌纲，γ-变形菌纲，巴斯德氏菌目，巴斯德菌科，嗜血菌属，是血管栓塞性脑膜脑炎等疾病的重要病原体。传播途径有呼吸道和泌尿生殖道等，可引起血管炎、败血症和多发性关节炎，经血到脊髓和脑可引起脑膜脑炎。致病机理是血管炎症和血管内血栓形成。血管炎，缺血性坏死是血血管栓塞性脑膜脑炎的病理特征。土拉霉素是高度有效的治疗与预防睡眠嗜血杆菌感染性疾病的药物。当疾病暴发流行时积极的监测、疫苗接种和适当的抗生素预防治疗是标准的推荐方法