| 摘要: |
| 采用超高效液相色谱-串联质谱法（UPLC-MS/MS）研究了氯苯胍在鸡组织中的残留消除规律。白来杭鸡以含氯苯胍500 mg/kg饲料饲喂7 d，停药后的第0、1、3、5、7天取其肌肉、肝脏、肾脏、皮和脂肪五种组织，采用UPLC-MS/MS法测定其残留状况。结果表明，氯苯胍在肌肉中残留量较小，代谢消除比较快，2 d后未检出；而在脂肪、皮和肝脏中残留量较大，代谢消除较慢。 |
| 关键词: 氯苯胍 鸡组织 残留消除 |
| DOI： |
| 投稿时间：2012-05-17修订日期：2012-07-04 |
| 基金项目: |
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| Depletion of Robenidine Residue in Chicken Tissues |
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| (Henan Institute of Veterinary Drug Control) |
| Abstract: |
| The depletion of robenidine residue in chicken tissues was studied by UPLC-MS/MS. After an oral dose of 500 mg per kilogram of robenidine for 7 days, the robenidine residue in chicken muscle was lower than that in other tissues, such as the fat，skin，kindey and liver，and it was not detected after 2 days. The results showed that robenidine in chicken tissues was of rapid absorption, and hard to be eliminate. |
| Key words: robenidine chicken tissues residue depletion |
