| 摘要: |
| 为评价黄芪多糖铁对缺铁性贫血小白鼠的补铁作用，采用苯肼诱导法制成小白鼠贫血模型。以硫酸亚铁和右旋糖酐铁为对照药物，在给药后第2天、第5天、第10天进行尾部采血，测定各组小白鼠不同时期血液中的红细胞数、血红蛋白、血清铁及血清铁蛋白含量。结果表明，黄芪多糖铁可以显著提高贫血小鼠的红细胞数、血红蛋白、血清铁及血清铁蛋白含量。 |
| 关键词: 黄芪多糖铁 贫血 小白鼠 药效学 |
| DOI： |
| 投稿时间：2010-12-20修订日期：2010-12-28 |
| 基金项目: |
|
| Studies on Pharmacodynamics of Mouse's Iron Deficiency Anemia Treated with Iron Astragalan |
| chenqingzhong |
| (Zhongao Bio-Technology Limited of Tianjin) |
| Abstract: |
| The studies evaluated the effects of iron supplementation iron astragalan on mouse’s iron deficiency anemia. Anemic domain model of mouse were prepared with phenylhydrazine. Using ferrous sulfate and iron dextran as control drugs, blood samples were taken from tail of mouse on the next day, the fifth day and the tenth day after treatments, at the same time the changes of blood biochemical indices included the content of erythrocyte, haemoglobin, serum iron and serum ferritin were determined and compared. Test results showed that iron astragalan could markedly increase the erythrocyte number, the content of hemoglobin，serum iron and serum ferritin. |
| Key words: Pharmacodynamics of Iron Astragalan on Mouse’s Iron Deficiency Anemia |
